Meet Spravato,
the only FDA-approved ketamine treatment for depression.
When the heavy fog of a depressive episode persists despite your best efforts, it is easy to feel like you have run out of options. For many individuals, traditional antidepressant medications provide a start, but not a solution. If you have tried two or more antidepressants without finding relief, you may be dealing with Treatment-Resistant Depression (TRD).
Spravato® nasal spray is a groundbreaking therapy that can provide rapid relief from severe depression using a ketamine derivative called esketamine. In 2019, Spravato was approved by the FDA to provide relief for those suffering from treatment-resistant depression (TRD).
Is Spravato right for you?
Treatment-Resistant Depression is a clinical diagnosis for individuals with Major Depressive Disorder who have not achieved remission after two or more adequate trials of antidepressant treatment. It suggests that the brain requires advanced interventions, such as intranasal esketamine or brain stimulation, to break the cycle of resistance.
Like anything else, there are potential side effects associated with treatment. Side effects will usually lessen with each session as your body adjusts to the medication. Some things to expect include nausea, drowsiness, headaches, dizziness, feelings of intoxication, and increased blood pressure. You can read more about potential contraindications or side effects in the Medication Guide linked at the bottom of the page. Some patients also can experience more extreme side effects, including hallucinations and feeling disconnected from themselves and their surroundings. Therefore, it is vital for treatment to be done in a safe and controlled environment where the patient can be monitored.
For the first four weeks, you can expect to come into the office twice weekly for treatment. During weeks 5 to 8 of treatment, you can expect to come in once weekly. For week 9 and after, depending on the efficacy/rate of remission, the patient and provider will determine if they should remain weekly or titrate down to biweekly.
Patients in this treatment program should expect to be at the office for a minimum of two hours on a treatment day. You will have your blood pressure taken prior to administration, halfway through treatment, and then one last time at the end. Staff will monitor you throughout your treatment period. Patients will need to have a ride home from treatment and should not drive or operate heavy machinery until having a restful night’s sleep.
The treatment is given as a spray through the nose. Each device contains a specific dose for each nostril. The dosing is determined by your provider during your first treatment; after that, you and your provider may decide whether to continue with the initial dose or to increase it.
Most major insurance plans provide coverage for Spravato® (esketamine) when it is prescribed for treatment-resistant depression or major depressive disorder with suicidal thoughts. Coverage requirements can vary depending on your specific insurance plan. Our team manages the entire insurance authorization process for you—including benefits verification and prior authorization—so you can focus on preparing for treatment rather than dealing with paperwork. We’ll also discuss any potential out-of-pocket costs with you before starting care, so there are no surprises.
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Patient Testimonials
“I love going here, the staff is amazing and the environment is safe and comfortable. I have struggled with depression for 33 years and can only now say that suicide is not a way out for me. This clinic and its staff made that possible and I will be eternally grateful. Thank you.”
A.B.
“Optimum has been accommodating and helpful with my treatment. They answer questions promptly and seem genuinely happy that the treatment is working for me. I finally feel good about myself and they made that possible.”
D.D.
“I feel that Spravato is going well and it is the first thing that has actually had a positive impact on my depressive symptoms in years.”
W.L.
“The staff has always made me feel valued and respected. I couldn’t ask for better people than there are here!”
D.G.
“Nowadays, when finding a good mental health care provider is like finding a unicorn, and ones that you’re able to make appointments less than a year in advance with are just as rare, Optimum is an absolute treasure of a clinic.”
L.D.
“Spravato is a helpful supplement to my mental health medications. A big thanks to the Optimum staff for their support!”
J.L.
No waitlists for new patients.
Start your journey today.
The Spravato® withMe program offers rebates to help cover eligible out-of-pocket costs. Based on your insurance benefits and deductible, eligible patients can receive assistance that reduces treatment expenses to as low as $10 per session.